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FLASH GENE

Symbol

OGDHL

contributors: mct - updated : 04-01-2022

HGNC name	oxoglutarate dehydrogenase-like
HGNC id	25590

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

NDDEDV

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   contributed to hepatocellular carcinoma (HCC) development and survival by regulating glutamine metabolic pathways tumoral       loss of function can contribute to cervical tumorigenesis via activation of the AKT1 signaling pathway

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	is a promising prognostic biomarker for HCC
Therapy target
	System Type Disorder Pubmed cancer digestive liver therapeutic target for HCC neurology neurodegenerative alzheimer may be a potential strategy for AD treatment

ANIMAL & CELL MODELS