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FLASH GENE
Symbol MAPK4 contributors: mct - updated : 28-11-2012
HGNC name mitogen-activated protein kinase 4
HGNC id 6878
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
highly upregulated in lung carcinomas
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerlung 
may be an attractive target for therapeutic treatment of invasive lung cancer
ANIMAL & CELL MODELS
  • loss of Erk3 in mouse retards intrauterine growth, as reflected by a marked reduction in fetal lung, heart, and liver weights, and by low body weight at birth