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FLASH GENE
Symbol GPX2 contributors: mct - updated : 19-10-2022
HGNC name glutathione peroxidase 2 (gastrointestinal)
HGNC id 4554
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in Pancreatic cancer tissues
tumoral     --over  
contributes to poor prognosis of hepatocellular carcinoma patients and helps to identify the high-risk hepatocellular carcinoma patients
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • may be considered as a novel biomarker in bladder cancer
  • Therapy target
    SystemTypeDisorderPubmed
    cancerendocrinepancreas
    GPX2 silencing could inhibit the Wnt pathway, subsequently suppress PC development
    cancerurinary 
    therapeutic target in bladder cancer
    ANIMAL & CELL MODELS