Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PTS | contributors: - updated : 27-12-2005 |
HGNC name | 6-pyruvoyltetrahydropterin synthase |
HGNC id | 9689 |
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Corresponding disease |
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Location | 11q23.1 Physical location : 112.097.087 - 112.104.693 | ||
Synonym name | |||
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Synonym symbol(s) | PTPS, FLJ97081 | ||
EC.number | 4.2.3.12 |
DNA |
TYPE | functioning gene |
STRUCTURE | 7.61 kb 6 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
|
mono polymer | homomer , hexamer |
HOMOLOGY |
Homologene |
FAMILY | PTPS family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth | |
intracellular,cytoplasm,cytoskeleton |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
1 zinc ion per subunit |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | PTSD |
related resource | 6-Pyruvoyl-tetrahydropterin synthase deficiency |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |