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FLASH GENE
Symbol RAP1GAP contributors: mct/shn - updated : 12-07-2012
HGNC name RAP1 GTPase activating protein
HGNC id 9858
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in pancreatic cancer, in progression
tumoral     --low  
in papillary thyroid carcinomas (Nellore 2009)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Knockdown of Rap1 or inhibition of its activity in retinal pigment epithelium reduces Transepithelial electrical resistance and electrical impedance of the retinal pigment epithelial monolayers