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FLASH GENE
Symbol HB-NA@ contributors: - updated : 19-05-2006
DNA
TYPE cluster
SPECIAL FEATURE
text embedded within an arrey of olfacting receptor genes
regulatory sequence Locus Control Region
motif repetitive sequence   ALU
text structure
  • site consisting of five functional genes in their order of developmental expression 5' - HbE1 - G1 - G2 -D - B 3' and the pseudogene GBBP1 (between G2 and D) with many Alu and like sequences
  • g1 a locus control region (LCR-B) conferring development and tissue specific expression,fetal hemoglobin B(alpha2,gamma2) expressed in liver and adult hemoglobin B(alpha2,gamma2) bone marrow
    • MAPPING cloned   linked   status provisional
    Map 5' - LCR-HB-B@ - HBE1 - HBG2 ,HBG1 ,HBBP1 ,HBD ,HBB - 3' -
    Text see INS , PTH
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS