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FLASH GENE
Symbol HAGH contributors: - updated : 03-03-2006
HGNC name hydroxyacyl glutathione hydrolase
HGNC id 4805
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
Homologene
FAMILY metallo-beta-lactamase superfamily
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • catalyzing the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    glyoxal pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binding two Zn2+ per subunit
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral       gain of function
    in superficial or invasive bladder cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS