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FLASH GENE
Symbol CACNG8 contributors: mct - updated : 26-03-2008
HGNC name calcium channel, voltage-dependent, gamma subunit 8
HGNC id 13628
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Cacng8
Homologene
FAMILY PMP22/EMP/MP20 family, CACNG subfamily
CATEGORY transport channel
SUBCELLULAR LOCALIZATION     plasma membrane
text distributed both in synaptic and extra-synaptic plasma membranes of the hippocampal neuron
basic FUNCTION
  • stabilizing the calcium channel in an inactive (closed) state
  • initiate translation from a non-AUG (CUG) start codon
  • have distinct roles in postsynaptic membranes under the regulation of different intracellular signaling pathways
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS