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FLASH GENE
Symbol POLR3K contributors: - updated : 12-05-2005
HGNC name polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
HGNC id 14121
Location 16p13.3      Physical location : 96.978 - 103.632
Synonym name RNA polymerase III subunit (hRPC11)
Synonym symbol(s) HRPC11, C11-RNP3, C11, RPC10
DNA
TYPE functioning gene
STRUCTURE 6.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC390662 16 similar to DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11; DEAD/H box-11 (CHL1-related helicase gene-1); yeast CHL1 homolog CXYorf1P 16p13.3 pseudogene of CXYorf1 POLR3K 16p13.3 polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa C16orf33 16p13.3 chromosome 16 open reading frame 33 RHBDF1 16p13.3 rhomboid family 1 (Drosophila) MPG 16p13.3 N-methylpurine-DNA glycosylase C16orf35 16p13.3 chromosome 16 open reading frame 35 HBZ 16p13.3 hemoglobin, zeta HBZP 16p13.3 hemoglobin, zeta pseudogene HBAP2 16p13.3 hemoglobin, alpha pseudogene 2 HBAP1 16p13.3 hemoglobin, alpha pseudogene 1 HBA2 16p13.3 hemoglobin, alpha 2 HBA1 16p13.3 hemoglobin, alpha 1 HBQ1 16p13.3 hemoglobin, theta 1 LUC7L 16p13.3 LUC7-like (S. cerevisiae) DKFZP761D0211 16p13.3 hypothetical protein DKFZp761D0211 PDIP 16p13.3 protein disulfide isomerase, pancreatic RGS11 16p13.3 regulator of G-protein signalling 11 ARHGDIG 16p13.3 Rho GDP dissociation inhibitor (GDI) gamma AXIN1 16p13.3 axin 1 MRPL28 16p13.3 mitochondrial ribosomal protein L28 TMEM8 16p13.3 transmembrane protein 8 (five membrane-spanning domains) LOC388197 16 hypothetical gene supported by BC028568 NME4 16p13 non-metastatic cells 4, protein expressed in DECR2 16p13.3 2,4-dienoyl CoA reductase 2, peroxisomal
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepancreas exocrine    
 stomach    
Reproductivefemale systemuteruscervix  
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
one ribbon-type zinc finger
mono polymer complex
HOMOLOGY
intraspecies homolog to TCEA1
Homologene
FAMILY archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
CATEGORY RNA associated , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • required for proper pausing and termination during transcription
  • synthesizing transfer and small ribosomal RNAs
  • CELLULAR PROCESS nucleotide, transcription, elongation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component a small essential subunit of RNA polymerase III
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
  • TCEA1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS