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FLASH GENE

Symbol

RHBDL1

contributors: np/ - updated : 05-09-2006

HGNC name	rhomboid, veinlet-like 1 (Drosophila)
HGNC id	10007

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	2.19 kb     7 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_003961 7 - 1559 NP_003952 - 438 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain         Homo sapiens Urinary kidney         Homo sapiens

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	seven transmembrane domains
	an intracellular N terminus

HOMOLOGY

interspecies

homolog to rhomboid Drosophila

Homologene

FAMILY

peptidase S54 family

CATEGORY

enzyme , regulatory

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

may be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS