Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TMEM204 contributors: npt/mct - updated : 23-08-2010
HGNC name transmembrane protein 204
HGNC id 14158
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a potential N-glycosylation site
  • four alpha-helical transmembrane domains
  • a C-terminal PDZ domain
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • novel regulator of KDR and FLT4 signaling pathways and of normal lymphatic vessel structure (Saharinen 2010)
  • modulator of KDR and FLT4 signals required for lymphatic vascular development (Saharinen 2010)
  • has an essential function in the lymphatic vasculature (Saharinen 2010)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacts with vascular endothelial growth factor receptor-2 KDR and FLT4 and attenuates the transcription factor CREB phosphorylation via these receptors (Saharinen 2010)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS