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FLASH GENE
Symbol PTX4 contributors: SGE/npt - updated : 13-07-2010
HGNC name pentraxin 4, long
HGNC id 14171
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one pentaxin domain
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • pentraxin (PTX) superfamily
    • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION extracellular
    text secreted
    basic FUNCTION
  • may be part of the humoral arm of innate immunity and behave as functional ancestor of antibodies by mediating agglutination, complement activation and opsonization (Martinez de la Torre 2010)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • binding two Ca2+ ions per subunit
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS