Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GJB4 contributors: mct/npt - updated : 17-09-2009
HGNC name gap junction protein, beta 4, 30.3kDa
HGNC id 4286
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Skin/Tegumentskin    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • N teminus cytoplasmic loop
  • two extracellular domain
  • four transmembrane domains
  • C terminus cytoplasmic
    • HOMOLOGY
    Homologene
    FAMILY
  • Gap junction channel family
  • connexin family
  • beta-type (group I) subfamily
    • CATEGORY regulatory , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    text integral to membrane
    basic FUNCTION
  • functional partners in the formation of keratinocyte cap junctions
  • regulation of epidermal differentiation and maintenance of epidermal homeostasis
    • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) EKV , PSEK2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS