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	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

SLC2A1

contributors: mct/ - updated : 15-08-2018

HGNC name	solute carrier family 2 (facilitated glucose transporter), member 1
HGNC id	11005

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SLC2A1 , DYT18 , DYT9

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in breast carcinoma with poor prognosis           mutations have been found in a family with paroxysmal exertion-induced dyskinesia tumoral     --over   highly expressed in HCC tissues and cell lines, promoting tumorigenesis tumoral     --over   in oral squamous cell carcinomas with poor prognosis tumoral   LOH     is significantly reduced in low-grade oligodendroglial tumors harboring LOH 1p

Susceptibility

to diabetic nephropathy

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive pancreas flavonoid apigenin inhibits SLC2A1 expression in pancreatic cancer cells

ANIMAL & CELL MODELS