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FLASH GENE
Symbol RAB23 contributors: mct/pgu - updated : 28-08-2017
HGNC name RAB23, member RAS oncogene family
HGNC id 14263
ASSOCIATED DISORDERS
corresponding disease(s) ACPS2
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   amplification    
in primary gastric tumors
tumoral     --over  
in Prostate cancer tissues and cell lines
tumoral     --over  
facilitates malignant cell growth and invasion in bladder cancer through the NFKB1 pathway
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • could serve as a biomarker that indicates the severity of FSGS
  • RAB23 expression is a useful indicator of metastatic potential for pancreatic duct adenocarcinoma
  • Therapy target
    SystemTypeDisorderPubmed
    cancerreproductiveprostate
    is a potential therapeutic target for PCa treatment
    cancerendocrinepancreas
    may be a new therapeutic target for pancreatic duct adenocarcinoma
    ANIMAL & CELL MODELS