Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PUM1

contributors: mct/npt - updated : 12-04-2022

HGNC name	pumilio homolog 1 (Drosophila)
HGNC id	14957

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SCA47

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in prostate cancer tumoral     --over   in ovarian cancer tissues was higher than that in normal tissues constitutional       gain of function in preeclampsia impairs trophoblast invasion by negatively regulating the expression of the lncRNA HOTAIR

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer reproductive prostate PUM1-CDKN1B regulatory axis may represent potential target for therapeutics development

ANIMAL & CELL MODELS