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FLASH GENE

Symbol

PTPN23

contributors: mct/npt - updated : 05-06-2019

HGNC name	protein tyrosine phosphatase, non-receptor type 23
HGNC id	14406

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

EIEE92

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   loss of PTPN23 may increase the activity of SRC and the phosphorylation status of the CDH1/CTNNB signaling complex to promote tumor growth and invasive behavior in breast cancer

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS