Symbol
| NDRG4
| contributors: mct - updated : 15-01-2010
|
HGNC name
| NDRG family member 4
|
HGNC id
| 14466
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
glioblastoma multiforme (GBM) cells | |
Variant & Polymorphism
|
| |
Candidate gene
| candidate tumor suppressor gene in colorectal cancer whose expression is frequently inactivated by promoter methylation and promoter methylation is a potential biomarker for the noninvasive detection of colorectal cancer |
Marker
Therapy target
| | |
| Tbx2 in the embryonic mouse heart at early stages of development throughout the myocardium of the heart tube both represses proliferation and impairs secondary heart field (SHF) progenitor cell deployment into the outflow tract (OFT), implicating the upregulation of Ndrg2 and downregulation of Ndrg4 expression |