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FLASH GENE

Symbol

LPXN

contributors: mct - updated : 14-01-2011

HGNC name	leupaxin
HGNC id	14061

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral fusion       with RUNX1 in an acute myeloid leukemia (AML) patient with t(11;21)(q12;q22) tumoral     --over   in prostate cancer (PCa) as compared with normal prostate tissue constitutional     --low   resulted in reduced osteoclast-mediated resorption

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target	could function as a putative target for therapeutic interventions of a subset of advanced prostate cancer

ANIMAL & CELL MODELS