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| natural Lpin1 mutant mouse strain fld displays a phenotype mainly characterized by transient postnatal fatty liver (before weaning) and persistent lipodystrophy | |
concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis  |
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hearts of mice lacking lipin 1 (fld mice) exhibit accumulation of phosphatidate |
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Lpin11Hubr rats developed hypomyelination and mild lipodystrophy |
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Lipin-1-deficient fld mice exhibit lipodystrophy characterized by dramatically reduced adipose tissue mass, absence of mature adipocytes, and metabolic dysregulation |
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loss of Lpin1 in mice inhibits adipogenesis at an early stage of differentiation and results in a lipodystrophic phenotype |
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lipin-1-related myopathy in the mouse is associated with a blockade in autophagic flux and accumulation of aberrant mitochondria |
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