Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

GFRA4

contributors: mct - updated : 10-01-2009

HGNC name	GDNF family receptor alpha 4
HGNC id	13821

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 6 - 1427 - 269 - Yang (2004) variant 2 5 - 1517 31.7 299 - Yang (2004)

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine thyroid         Nervous brain diencephalon hypothalamus       brain basal nuclei caudate nucleus     nervous brain basal nuclei putamen

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine

cell lineage	malignant thyroid medullary cell lines
cell lines
fluid/secretion

at STAGE

physiological period

embryo

Text	brain, bladder

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

hydrophobic leader sequence

HOMOLOGY

Homologene

FAMILY

GDNF receptor family

CATEGORY

receptor

SUBCELLULAR LOCALIZATION	extracellular
	plasma membrane

basic FUNCTION

functional, N-glycosylated, glycosylphosphatidylinositol (GPI)-anchored protein, which mediates persephin (PSPN)-induced phosphorylation of RET

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS