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FLASH GENE

Symbol

BET1

contributors: npt/ - updated : 23-11-2005

HGNC name	blocked early in transport 1 homolog (S. cerevisiae)
HGNC id	14562

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	12.69 kb     4 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed BET1 4 - 3161 13.2 118 - -

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver       moderately Nervous brain       moderately Reproductive male system prostate     moderately Respiratory lung       moderately Urinary kidney       highly

cell lineage
cell lines	choriocarcinoma
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a t-SNARE coiled-coil homology domain

HOMOLOGY

interspecies	homolog to yeast S.cerevisiae bet1
	ortholog to murine Bet1
	homolog to xenopus Xl.17630
	homolog to rattus bet1

Homologene

FAMILY

BET1 family

CATEGORY

structural protein , transport

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,endoplasmic reticulum
	intracellular,cytoplasm,organelle,Golgi
text	type IV membrane protein

basic FUNCTION

participating in vesicular transport from the endoplasmic reticulum to Golgi apparatus

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

cellular trafficking transport

text	protein transport

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS