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FLASH GENE
Symbol BET1 contributors: npt/ - updated : 23-11-2005
HGNC name blocked early in transport 1 homolog (S. cerevisiae)
HGNC id 14562
Location 7q21.1-q22      Physical location : 93.620.999 - 93.633.690
Synonym name
  • BET1 homolog (S. cerevisiae)
  • Golgi vesicular membrane trafficking protein p18
  • Bet1p homolog
  • blocked early in transport 1
    • Synonym symbol(s) HBET1, DKFZp781C0425
    DNA
    TYPE functioning gene
    STRUCTURE 12.69 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 3161 13.2 118 - -
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver   moderately
    Nervousbrain   moderately
    Reproductivemale systemprostate  moderately
    Respiratorylung   moderately
    Urinarykidney   highly
    cell lineage
    cell lines choriocarcinoma
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a t-SNARE coiled-coil homology domain
    • HOMOLOGY
    interspecies homolog to yeast S.cerevisiae bet1
    ortholog to murine Bet1
    homolog to xenopus Xl.17630
    homolog to rattus bet1
    Homologene
    FAMILY
  • BET1 family
    • CATEGORY structural protein , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    text type IV membrane protein
    basic FUNCTION
  • participating in vesicular transport from the endoplasmic reticulum to Golgi apparatus
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text protein transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS