Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PNPLA6 | contributors: npt/shn - updated : 25-09-2012 |
HGNC name | patatin-like phospholipase domain containing 6 |
HGNC id | 16268 |
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PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
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|
conjugated | GlycoP |
HOMOLOGY |
interspecies | ortholog to Pnpla6, Mus musculus |
ortholog to Pnpla6, Rattus norvegicus | |
ortholog to PNPLA6, Pan troglodytes |
Homologene |
FAMILY | |
|
CATEGORY | enzyme , regulatory |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | lipid/lipoprotein |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
inhibited by | protein kinase C activation with phorbol 12-myristate 13-acetate (PMA) stimulation |
ASSOCIATED DISORDERS |
corresponding disease(s) | SPG39 |
Other morbid association(s) |
|
Susceptibility | to organophosphorus compound-induced delayed neuropathy |
Variant & Polymorphism other | mutation increasing the risk of organophosphorus compound-induced delayed neuropathy |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |