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FLASH GENE

Symbol

FTH1

contributors: mct/npt - updated : 16-02-2018

HGNC name	ferritin, heavy polypeptide 1
HGNC id	3976

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

IRO

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in gastric cancer constitutional       loss of function in most cells of the forebrain including cells of the choroid plexus caused accumulation of cerebrospinal fluid in the lateral ventricles and the subarachnoid space tumoral     --over   is closely related to the development of leukemia/lymphoma, which could have implications for the prevention of malignant hematologic diseases

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	is a novel and reliable marker for macrophages and early erythroid precursors, and may be of clinical utility in the diagnosis of diseases associated with these two cell types
Therapy target

ANIMAL & CELL MODELS