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FLASH GENE

Symbol

CTPS2

contributors: mct - updated : 28/11/2008

HGNC name	CTP synthase II
HGNC id	2520

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_019857 19 - 3844 NP_062831 65 586 - 2006 17081983 NM_175859 19 - 3947 NP_787055 - 586 - 2006 17081983 NM_001144002 19 - 4334 NP_001137474 - 586 - -

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland       highly Lymphoid/Immune lymph node       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

two major phosphorylation sites, Ser(568) and Ser(571)

HOMOLOGY

Homologene

FAMILY

CTP synthase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic

basic FUNCTION	converting uridine triphosphate (UTP) to CTP
	generates the CTP required for the synthesis of nucleic acids and membrane phospholipids

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

text	basic converting urideme triphosphate (UTP)

PATHWAY

metabolism

purine/pyrimidine

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

Other

phosphorylated by mammalian protein kinase A

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS