| basic FUNCTION
| is not only a phagocytic receptor, but also a potent inhibitor of the alternative pathway convertases  |
|
T cells can opposite T cell hyporesponsiveness through dampening VSIG4 inhibitory signals from macrophages and thus maintain their anti-viral function in chronic HBV infection (CHB) |
|
B7 family-related macrophage protein that has the capacity to inhibit T-cell activation, and has a potential role in the development of lung cancer |
|
acts as a co-inhibitory ligand to negatively regulate T cell proliferation and cytokine production, and its expression is restricted to macrophages |
|
functions as a macrophage pattern recognition receptor to directly bind and capture blood-borne Gram-positive bacteria |
|
macrophage-associated VSIG4 plays a negative role in helper T cell-dependent isotype switching by inhibiting helper T cell activation and differentiation, and suppressing the isotype switching-inducing cytokine production in antigen-primed CD4(+) helper T cells |
|
dual functionality: a negative regulator of T cell activation and a receptor for the complement components C3b and C3c |
|
B7 family-related macrophage protein with the capacity to inhibit T-cell activation, having a potential role in cancer |
|
inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism |
