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FLASH GENE
Symbol POLR2K contributors: npt/ - updated : 28-11-2007
HGNC name polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
HGNC id 9198
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • highly conserved sequence in C terminal half with an invariant motif corresponding to a canonical zinc binding domain
    • HOMOLOGY
    interspecies homolog to Sc10 alpha
    Homologene
    FAMILY
  • archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family
    • CATEGORY enzyme , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • catalyzing the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • subunit of RNA polymerase II and may be of POLRI and POLRIII
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS