Symbol
| PROKR1
| contributors: mct/npt - updated : 07-07-2020
|
HGNC name
| prokineticin receptor 1
|
HGNC id
| 4524
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --over
|  
|
PROK1 and PROKR1 expression is elevated in decidua during early pregnancy and that PROK1-PROKR1 interaction regulates expression of a host of implantation-related genes (Evans 2008) | |
Susceptibility
|
to recurrent miscarriage (RM) |
Variant & Polymorphism
other
| PROKR1 (I379V) variant conferred lower risk for RM and may play protective roles in early pregnancy by altering calcium signaling and facilitating cell invasiveness ![](pubmed.jpg) |
|
|
Candidate gene
Marker
Therapy target
| may represent a novel therapeutic target to limit myocardial injury following ischemic events (Urayama 2007) |
| | |