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FLASH GENE

Symbol

FBP2

contributors: npt/ - updated : 20-06-2006

HGNC name	fructose-1,6-bisphosphatase 2
HGNC id	3607

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	9q22.3      Physical location : 97.321.004 - 97.356.075
Synonym name	hexosediphosphatase
	HCV F protein-binding protein 2
	muscle fructose-bisphosphatase
	hepatitis C virus F protein-binding protein 2
Synonym symbol(s)	FBPase, MGC142192
EC.number	3.1.3.11, 2.7.1.11

DNA

TYPE	functioning gene
STRUCTURE	35.00 kb     7 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed FBP2 7 - 1332 36.6 339 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Digestive intestine large intestine colon     Nervous brain         Respiratory lung

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal     Nervous peripherous

cells

System Cell Pubmed Species Stage Rna symbol Nervous optic nerve

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to murine Fbp2

Homologene

FAMILY	FBPase family
	pecanex family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION

gluconeogenesis regulatory enzyme catalyzing the hydrolysis of fructose 1.6 biphosphate

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

carbohydrate

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

activated by

thyroid hormones

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS