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FLASH GENE
Symbol KCNK4 contributors: mct - updated : 22-10-2014
HGNC name potassium channel, subfamily K, member 4
HGNC id 6279
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four transmembrane segments
  • two pore forming regions (P domains)
  • two P domains arranged like a tandem of inward rectifier channels
    • HOMOLOGY
    intraspecies homolog to TASK1
    Homologene
    FAMILY
  • two pore domain family of potassium channel family
    • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling neurotransmission
    synaptic transmission
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • KCNK2, KCNK4, KCNK10 interact with partner proteins that influence their activity and their plasma membrane expression
    • cell & other
    REGULATION
    activated by arachidonic acid,unsatured fatty acid,neuroprotective drug riluzole
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS