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FLASH GENE
Symbol CDH20 contributors: - updated : 03-05-2005
HGNC name cadherin 20, type 2
HGNC id 1760
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal hydrophobic domain
  • five extracellular cadherin repeats
  • four cysteines in the most proximal (MPED)
  • a transmembrane segment
  • a highly conserved cytoplasmic tail required for interactions
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Cdh7
    Homologene
    FAMILY
  • cadherin superfamily of calcium dependent cell-cell adhesion glycoproteins
    • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,adherens
    basic FUNCTION
  • involved cell-cell or cell-ECM interactions
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
  • hemophilic, calcium dependent interactions
  • interacting by its C terminus with the cytoskeleton via beta-catenin
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS