Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ARNTL2 | contributors: mct - updated : 17-09-2011 |
HGNC name | aryl hydrocarbon receptor nuclear translocator-like 2 |
HGNC id | 18984 |
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Location | 12p11.23 Physical location : 27.485.987 - 27.573.466 |
Synonym name | |
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Synonym symbol(s) | BMAL2, MOP9, CLIF, PASD9, bHLHe6, MGC149671, MGC149672 |
DNA |
TYPE | functioning gene |
STRUCTURE | 87.48 kb 17 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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text | three novel transcripts differing in their N terminus (PMID: 12738229) |
EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | brain (thalamus, hypothalamus) |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | heteromer , dimer |
HOMOLOGY |
interspecies | homolog to murine Arntl2 (73.08 pc) |
homolog to Drosophila circadian factor CYCLE (50.00 pc) |
intraspecies | paralog to CLOCK |
homolog to ARNT |
Homologene |
FAMILY |
CATEGORY | transcription factor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus,chromatin/chromosome |
basic FUNCTION | |
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CELLULAR PROCESS | nucleotide, transcription |
PHYSIOLOGICAL PROCESS | circadian |
PATHWAY |
metabolism |
signaling | signal transduction |
a component | colocalizing and heterodimerizing with CLOCK, HF1A, NPAS2 (MOP4) |
INTERACTION |
DNA | binding to an E-box element (5'-GTGCAC-3') |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |