Symbol
| UGT1A6
| contributors: mct/npt - updated : 01-10-2014
|
HGNC name
| UDP glucuronosyltransferase 1 family, polypeptide A6
|
HGNC id
| 12538
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --over
|  
|
in undifferentiated cells (Siissalo 2008) | |
Susceptibility
|
resistance to aspirin to bladder cancer |
Variant & Polymorphism
other
| UGT1A6*2 may confer more rapid glucuronidation of salicylic acid (Feher 2009) |
|
rs17863783 may protect from bladder cancer by increasing the removal of carcinogens from bladder epithelium by the UGT1A6.1 protein |
|
|
Candidate gene
Marker
Therapy target
| | | |