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FLASH GENE
Symbol SYPL1 contributors: - updated : 05-10-2005
HGNC name synaptophysin-like protein
HGNC id 11507
Location 7q22.3      Physical location : 105.730.952 - 105.753.057
Genatlas name pantophysin
Synonym symbol(s) H-SP1, SYPL
DNA
TYPE functioning gene
STRUCTURE 22.00 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
Map cen - D7S2545 - D7S658 - D7S2446 - D7S2840 - SYPL1 - D7S2420 - D7S2783
Authors GeneMap (99)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four putative transmembrane segments (TM4),
  • intracytoplasmic N and C termini
  • mono polymer homomer , dimer , tetramer
    HOMOLOGY
    Homologene
    FAMILY synaptophysin/synaptobrevin family
    CATEGORY secretory , signaling neurotransmitter
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text membrane of synaptic vesicles
    basic FUNCTION may be involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling neurotransmission
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS