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FLASH GENE

Symbol

DONSON

contributors: KTN/npt - updated : 05/11/2008

HGNC name	downstream neighbor of SON
HGNC id	2993

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	opposite orientation, tail to tail
text	in tail-to-tail orientation with SON
STRUCTURE	10.80 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

Map	see IFNAR1

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed DONSON 10 - 2189 62.6 566 - -

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Hearing/Equilibrium ear       predominantly Reproductive female system uterus cervix   highly   female system breast mammary gland   moderately Urinary bladder       moderately

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	homolog to dog DONSON (86.4 pc)
	homolog to chimpanzee DONSON (99.3 pc)
	homolog to cow DONSON (87.3 pc)
	homolog to rattus Donson (79.5 pc)
	homolog to murine Donson (78 pc)

Homologene

FAMILY

DONSON family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	playing an essential role for DNA amplification in the ovary
	required for cell proliferation during development
	acting as a transcription repressor

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

development

text	multicellular organismal development

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS