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FLASH GENE
Symbol ATRN contributors: mct - updated : 06-10-2017
HGNC name attractin
HGNC id 885
ASSOCIATED DISORDERS
corresponding disease(s) HLD14
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • suppression of obesity in mouse
  • age-related Atrn gene progressively loses its function and can cause testis vacuolation and impaired sperm function, which may be responsible for the impairment of male reproductive ability
  • Mahogunin ring finger-1 (Mgrn1) and Attractin (Atrn) null mutant mice accumulate vacuoles throughout the brain that appear very similar to those associated with prion disease