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FLASH GENE
Symbol ZIM2 contributors: - updated : 15-07-2004
HGNC name zinc finger, imprinted 2
HGNC id 12875
DNA
TYPE functioning gene
STRUCTURE 28.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text sharing identical 5' end composed of seven small exons with PEG3
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text moderatly in kidney and brain
IMPRINTING maternally
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal leucine rich domain (shared exon 3)
  • a central KRABA domain
  • 13 C terminal zinc finger motifs (encoded by the not shared exons)
    • HOMOLOGY
    Homologene
    FAMILY krueppel C2H2-type zinc-finger protein family
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be playing a role in renal development
  • involved in the repair of the kidney after ischemia- reperfusion or folic acid administration
    • CELLULAR PROCESS nucleotide, transcription
    protein
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS