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FLASH GENE

Symbol

SH2D2A

contributors: mct - updated : 06-04-2014

HGNC name	SH2 domain protein 2A
HGNC id	10821

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to Guillain-Barré syndrome multiple sclerosis

Variant & Polymorphism other	association with a homozygous genotype for a low repeat number of tandem GA in the SH2D2A gene in Guillain-Barré syndrome

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Tsad-deficient murine thymocytes failed to respond to CXCL12 with increased Itk phosphorylation, and displayed reduced actin polymerization and cell migration responses