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FLASH GENE
Symbol SND1 contributors: mct/npt/pgu - updated : 16-10-2014
HGNC name staphylococcal nuclease and tudor domain containing 1
HGNC id 30646
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in recurrent androgen-insensitive prostate cancer tissues
tumoral     --over  
in colon cancers (SND1 may thus occur at a very early stage in colon carcinogenesis and contribute to the posttranscriptional regulation of key players in colon cancer development, including APC and beta-catenin)
tumoral     --over  
in multiple cancers, including hepatocellular carcinoma (HCC)
Susceptibility
Variant & Polymorphism SNP
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerreproductiveprostate
promising prostate cancer biomarker and therapeutic target
cancerdigestiveliver
targeted inhibition of SND1 could be an effective way to counteract hepatocellular carcinoma
ANIMAL & CELL MODELS