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| Homozygous animals for disrupted emilin1 gene were fertile and showed no obvious abnormalities; however, histologic and ultrastructural examination revealed alterations of the elastic fibers in aorta and skin | |
Emilin1 knockout animals display increased blood pressure, increased peripheral vascular resistance, and reduced vessel size |
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Genetic ablation of Emilin1 in mice causes elastic fiber defects in aorta and skin resulting in vascular abnormalities such as increased blood pressure, increased peripheral vascular resistance, and reduced vessel size |
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genetic ablation of Emilin1 in mice causes elastic fiber defects in aorta and skin resulting in vascular abnormalities such as increased blood pressure, increased peripheral vascular resistance, and reduced vessel size  |