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FLASH GENE
Symbol ZNF256 contributors: SGE/npt - updated : 16-05-2008
HGNC name zinc finger protein 256
HGNC id 13049
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connectivebone   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticmature hematopoietic
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a KRAB (Krüppel associated box) domain
  • 14 C2H2-type zinc fingers
    • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to chimpanzee ZNF256 (99.4pc)
    Homologene
    FAMILY
  • krueppel C2H2-type zinc finger protein family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • transcriptional repressor activity
    • CELLULAR PROCESS cell life, proliferation/growth
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • ion Zn2+
    • protein
  • interacting with TRIM28, its co-repressor
    • cell & other
    REGULATION
    induced by GDNF
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS