Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CRYAB | contributors: mct/shn - updated : 02-10-2012 |
HGNC name | crystallin, alpha B |
HGNC id | 2389 |
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Corresponding disease |
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Location | 11q23.1 Physical location : 111.779.349 - 111.782.473 | ||||||||
Synonym name | |||||||||
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Synonym symbol(s) | CRYA2, CTPP2, CRAB, HSPB5 |
DNA |
TYPE | functioning gene |
STRUCTURE | 3.12 kb 3 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D11S1893 - D11S1793 - CRYAB - D11S4192 - D11S1347 - qter |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | fetal eye, lens, umblilical cord |
PROTEIN |
PHYSICAL PROPERTIES | basic | |
STRUCTURE |
mono polymer | heteromer , aggregate , complex |
HOMOLOGY |
interspecies | ortholog to Cryab, Rattus norvegicus |
ortholog to Cryab, Mus musculus | |
ortholog to CRYAB, Pan troglodytes | |
ortholog to cryaba, Danio rerio |
intraspecies | homolog to CRYAA |
Homologene |
FAMILY | |
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CATEGORY | chaperone/stress , motor/contractile |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,cytoplasm | |
intracellular,nucleus |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | sensory transduction/vision |
photoreception |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | DRM , CPP2 , CMD1II , MMFIH |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |