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FLASH GENE
Symbol CDK5R2 contributors: npt/mct - updated : 24-06-2016
HGNC name cyclin-dependent kinase 5, regulatory subunit 2 (p39)
HGNC id 1776
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal p10 regions
  • C-terminal CDK5 activation domains (AD)
    • mono polymer heteromer , dimer
    HOMOLOGY
    intraspecies paralog to CDK5R1
    Homologene
    FAMILY
  • cyclin-dependent kinase 5 activator family
    • CATEGORY enzyme , regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • neuronal activator of CDK5
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterodimerizing with CDK5
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other cleaved to p29 by Ca2+ calpain
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS