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FLASH GENE
Symbol CDK5R2 contributors: npt/mct - updated : 24-06-2016
HGNC name cyclin-dependent kinase 5, regulatory subunit 2 (p39)
HGNC id 1776
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland    
 pancreas    
Nervousbrain    
Respiratorylung    
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal p10 regions
  • C-terminal CDK5 activation domains (AD)
  • mono polymer heteromer , dimer
    HOMOLOGY
    intraspecies paralog to CDK5R1
    Homologene
    FAMILY
  • cyclin-dependent kinase 5 activator family
  • CATEGORY enzyme , regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • neuronal activator of CDK5
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterodimerizing with CDK5
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other cleaved to p29 by Ca2+ calpain
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS