Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TSFM contributors: - updated : 11-10-2006
HGNC name Ts translation elongation factor, mitochondrial
HGNC id 12367
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
N terminal mitochondrial signal peptide
HOMOLOGY
interspecies homolog to bovine EF-TSMT
homolog to Drosophila CG6412
homolog to C.elegans F55C5.5
Homologene
FAMILY EF-TS family
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
basic FUNCTION
  • inducing the exchange of GDP to GTP
  • guanine nucleotide exchange factor that binds to the TUFM
    • guanosine diphosphate (GDP) complex, promoting the release of GDP and the formation of a stable TUFM
    TSFM heterodimer
    CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component associated with the TUFM.GDP complex
    INTERACTION
    DNA
    RNA binding to aminoacyl-tRNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) COXPD2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS