Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TSFM | contributors: - updated : 11-10-2006 |
HGNC name | Ts translation elongation factor, mitochondrial |
HGNC id | 12367 |
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Corresponding disease |
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Location | 12q13-q14 Physical location : 58.176.527 - 58.196.639 | ||
Synonym symbol(s) | EFTS, EFTSMT |
DNA |
TYPE | functioning gene |
STRUCTURE | 13.00 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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motif | repetitive sequence ALU long interspersed repetitive elements |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
| N terminal mitochondrial signal peptide |
HOMOLOGY |
interspecies | homolog to bovine EF-TSMT |
homolog to Drosophila CG6412 | |
homolog to C.elegans F55C5.5 |
Homologene |
FAMILY | EF-TS family |
CATEGORY | RNA associated |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria |
basic FUNCTION | |
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guanosine diphosphate (GDP) complex, promoting the release of GDP and the formation of a stable TUFM | |
TSFM heterodimer |
CELLULAR PROCESS | protein, translation/synthesis |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | associated with the TUFM.GDP complex |
INTERACTION |
DNA |
RNA | binding to aminoacyl-tRNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | COXPD2 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |