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FLASH GENE

Symbol

HEYL

contributors: npt/mct - updated : 11-01-2012

HGNC name	hairy/enhancer-of-split related with YRPW motif-like
HGNC id	4882

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function inactivation of HEY1 and HEYL, two primary target genes of Notch, causes severe heart malformations, including membranous ventricular septal defects and dysplastic atrioventricular and pulmonary valves tumoral     --over   represses AR-regulated genes and hormone-dependent prostate cancer cell line growth

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS