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FLASH GENE
Symbol NT5M contributors: npt/ - updated : 07-04-2006
HGNC name 5',3'-nucleotidase, mitochondrial
HGNC id 15769
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Endocrinepancreas   lowly
Nervousbrain    
Urinarykidney   lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumcardiac  
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • mitochondrial leader peptide
    • HOMOLOGY
    interspecies homolog to murine Nt5c
    intraspecies homolog to DNT1
    Homologene
    FAMILY
  • 5'(3')-deoxyribonucleotidase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • potential protector of mt DNA from over production of dTTP
    • CELLULAR PROCESS nucleotide
    protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism nucleic , purine/pyrimidine
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS