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FLASH GENE
Symbol SCT contributors: - updated : 18-02-2006
HGNC name secretin
HGNC id 10607
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Digestiveintestinesmall intestineduodenum lowly
 intestinesmall intestinejejunum lowly
Nervousbrain   lowly
Reproductivemale systemtestis   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • prosecretin made of a signal peptide
  • the bioactive mature secretin
  • a C terminal tail
    • HOMOLOGY
    interspecies homolog to murine Sct
    Homologene
    FAMILY glucagon family
    CATEGORY signaling hormone
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • stimulating the secretion of bicarbonate-rich pancreatic fluids and inhibiting HCL production by the stomac
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS digestion
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by the Sp1/Sp3 ratio and the methylation status of the promoter
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autistic disorders
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS